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New Flea, Tick and Parasite Control
With spring right around the corner, we thought it would be a good time to introduce our newest option for canine heartworm prevention! Similar to other heartworm preventatives, Trifexis� is a once monthly oral flavored tablet. The most exciting aspect of Trifexis is that unlike other heartworm preventatives, Trifexis� can also kill adult fleas! It contains two active ingredients instead of one, so protects your dog from heartworms, intestinal parasites and kills fleas for the entire month! It can be safely combined with a topical product, such as Vectra, for complete protection against our most common parasites-including fleas, ticks, biting flies, lice, heartworms, hookworms, roundworms and whipworms! Trifexis is for dogs only; ask us for more information about products to keep your kitties protected!
Re mind Yourself when your pet is due for medications by setting up Automatic Reminders and Downloading these other tools and toys for Dog Lovers. .
3 types of parasite protection.
2 trusted active ingredients.
1 chewable tablet.
Trifexis�combines two proven active ingredients to provide three types of parasite protection in an FDA-approved monthly, chewable tablet for dogs.

Trifexis� controls fleas
Trifexis� (spinosad + milbemycin oxime) offers month-long flea protection in a chewable, flavored tablet. Trifexis:
- Kills fleas and prevents flea infestations for a full month
- Starts killing adult fleas within 30 minutes
- Kills 100% of fleas in 4 hours in a controlled laboratory study
- Kills fleas before they can lay eggs
The active flea control ingredient in Trifexis�, spinosad, kills fleas by targeting their nervous systems, resulting in paralysis and rapid death.
Trifexis� prevents heartworm disease
Trifexis�prevents heartworm disease caused by Dirofilaria immitis in dogs. The active ingredient in Trifexis for heartworm control, milbemycin oxime, is a proven active ingredient used by veterinarians for years.
Canine heartworm incidence

Map � American Heartworm Society: http://www.heartwormsociety.org/ The severity of heartworm
incidence as shown in this map is based on the average number of cases per reporting clinic.
Some remote regions of the United States lack veterinary clinics; therefore, there are no reported
cases from these areas.
For more information about heartworm, visit our Heartworm Disease page, under Pet Library and Encyclopedia.
Trifexis� treats and controls intestinal parasites
Trifexis� treats and controls three types of intestinal parasites:
- adult hookworm infections (Ancylostoma caninum)
- adult roundworm infections (Toxocara canis & Toxascaris leonina)
- adult whipworm infections (Trichuris vulpis)
For more about intestinal parasites, visit our Intestinal Parasite Control and Treatment page,under Pet Library and Encyclopedia.
Green Chemistry
The introduction of spinosad for use in agriculture resulted in the receipt of a Presidential Green Chemistry Challenge Award in 1999 from the U.S. Environmental Protection Agency. The award was presented to Dow AgroSciences LLC in the category of ?Designing Safer Chemicals? for the introduction of spinosad as an insect control product for use on crops. This award demonstrates that spinosad as a technology for insect control has a favorable environmental profile. This award is not relevant to the safety and efficacy of Trifexis�, nor does it confer any environmental benefit to Trifexis�
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